Ora lo stesso team è riuscito ad inserire le basi extra in una tratto di DNA codificante, e a farlo esprimere: il gene è stato trascritto in un RNA e tradotto in una proteina funzionante, ancorché contenente aminoacidi non naturali...
A group of researchers from La Jolla, California, published about 3 years ago a work describing a modified strain of the E. coli bacterium into which they incorporated two extra bases, called X and Y, within the DNA.
Now the same team was able to insert the extra bases in a coding stretch of DNA, and to make it express: the gene was transcribed into an RNA and translated into a working protein, although containing non-natural amino acids...
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